Gemfibrozil and Atorvastatin
Affecting DrugC10AB04  Gemfibrozil
Affected DrugsC10AA05  Atorvastatin
Gemfibrozil and lovastatin used together can cause severe myopathy and rhabdomyolysis. Combined use of gemfibrozil or clofibrate with other HMG-CoA reductase inhibitors may increase the risk of this side effect as well. If this combination must be used, the patient should be instructed to report symptoms of muscular pain, weakness, or tenderness. If creatine kinase is elevated, the drugs should be discontinued.