- Lansoprazole and Clopidogrel

Lansoprazole and Clopidogrel

Posted about 1 year ago by David Chan (MEDIUM significance )

Affecting Drugs

A02BC03 Lansoprazole
A02BC05 Esomeprazole
A02BC01 Omeprazole
A02BC02 Pantoprazole

Effect

Inhibits

Affected Drug

B01AC04 Clopidogrel

Details

PPI use reduces benefit of clopidogrel post-MI
The use of a proton pump inhibitor (PPI) other than pantoprazole (Protonix) is associated with a significantly increased risk of recurrent myocardial infarction (MI) in patients already taking clopidogrel (Plavix). Consider prescribing pantoprazole if a PPI is needed in a post-MI patient. (LOE = 3b)

MyDrugRef