Posted Saturday 09 October 2010 - 22:09 PM by Cam Ross
- P01BA02 Hydroxychloroquine
BaselineBaseline: If >40yrs or pt has eye disease then needs baseline ophthalmologic exam including fundoscopy and visual fields. Ensure appropriate contraception for female patients during child bearing years. Avoid doses > 6.5 mg/kg as increased risk of retinopathy.
Follow-upFollow-up: Annual ophthalmologic examination including fundoscopy and visual fields for all patients. Review contraception and ensure appropriate dosing. Monitor pt weight if close to 55 kg using usual doses, decrease usual dose with lower weights to decrease toxicity
Interaction no sig drug interactions
|Notes -- All: |
baseline eye disease
|Ocular||Ophthalmology exam incl fundoscopy + visual fields if age > 40 or baseline eye disease||Annual ophthalmology assessment||corneal & retinal deposition (dose and duration dependent)||3-4% with 10 years of use||Avoid doses greater than 6.5 mg/kg as increased risk of retinopathy; D/C if retinopathy occurs|
- Repchinsky C, editor. Compendium of Pharmaceutical and Specialties, 2006 edition. Ottawa: The Canadian Pharmacists Association; 2006. ; Wallace DJ. Antimalarial drugs in the treatment of rheumatic disease. In: UpToDate, Basow, DS (Ed) UpToDate, Waltham, MA, 2010.
- Wallace DJ. Antimalarial drugs in the treatment of rheumatic disease. In: UpToDate, Basow, DS (Ed) UpToDate, Waltham, MA, 2010.